Latent Cerebral Toxoplasma Gondii Infection Induces the Kynurenine Pathway and Production of Neurotoxic Metabolites.

paru le: 07/07/2026

Kezai, Amir Mohamed et al.

International journal of tryptophan research : IJTRvol. 19 11786469261461119. 3 Jul. 2026, doi:10.1177/11786469261461119

The kynurenine pathway (KP) has been implicated in a broad range of neurological disorders. KP activation in brain resident immune cells, including astrocytes and microglia, contributes to the release of neuroactive metabolites with strong impact on neuronal functions.

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