Latent Cerebral Toxoplasma Gondii Infection Induces the Kynurenine Pathway and Production of Neurotoxic Metabolites.
Kezai, Amir Mohamed et al.
International journal of tryptophan research : IJTRvol. 19 11786469261461119. 3 Jul. 2026, doi:10.1177/11786469261461119
The kynurenine pathway (KP) has been implicated in a broad range of neurological disorders. KP activation in brain resident immune cells, including astrocytes and microglia, contributes to the release of neuroactive metabolites with strong impact on neuronal functions.