Toll-like receptor 5 agonist is a potent adjuvant for intradermal vaccination.

Published: 04/20/2026

Sirard, Jean-Claude et al - Vaccine/, vol. 80 128543. 4 Apr. 2026, doi:10.1016/j.vaccine.2026.128543

Flagellin, the key structural protein of bacterial flagella, is known to stimulate Toll-like receptor 5 (TLR5) signaling, making it an effective adjuvant for nasal, intramuscular, or subcutaneous routes of vaccination.

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