Laurence Cocquerel
CNRS research director (DR1)

Laurence's ORCID
Laurence's contact

 

TRAINING

  • 2006 HDR-habilitation to conduct research, University of Lille, France
  • 2001 PhD in Microbiology-Virology, Sorbonne University, France.

POSITIONS HELD

  • 2023 - present : Research director (CNRS-DR1).
    Center for Infection and Immunity of Lille, France.
    Leader of the group “Molecular and Cellular Virology of Hepatitis E”
  • 2016-2023 : Research director (CNRS-DR2).
    Center for Infection and Immunity of Lille, France.
    Leader of the group “Molecular and Cellular Virology of Hepatitis E”
  • 2007-2015 : Senior researcher (CNRS-CR1)
    Center for Infection and Immunity of Lille, France.
    Leader of the group “Modulation of Hepatitis C Virus entry and cellular processes”
  • 2003-2007 : Junior researcher (CNRS-CR2)
    Institut de Biologie de Lille / Institut Pasteur de Lille, France
    Leader of the group “Modulation of Hepatitis C Virus entry and cellular processes”
  • 2001-2003 : Post-doctoral researcher.
    Stanford University, Palo Alto, USA
    Research project : study of the interaction between Hepatitis C Virus glycoproteins and the tetraspanin CD81.
    PI : Pr. Shoshana Levy
  • 1997-2001 : PhD student
    institut de Biologie de Lille / Institut Pasteur de Lille, France
    Research project : characterization of the transmembrane domains of Hepatitis C virus E1 and E2 glycoproteins
    PI: Jean Dubuisson

COMPETENCES / EXPERTISE

Expert member of the ANRS-MIE scientific evaluation committee CSS12. Evaluation of contracts and grants for basic research on viral hepatitis. 
Coordinator of the national Hepatitis E network - ANRS-MIE / AC42 
Member of the scientific advisory board of the AGIR Unit (Infectious agents, resistance and chemotherapy), UR 4294, Université de Picardie Jules Verne, Amiens, France.
Member of the steering committee of the Center for Infection and Immunity of Lille, Lille, France.
Member of the Pasteur Network, Scientific Working Group on R&D&I Diagnostics
Research Expertise :

  • Molecular and cellular virology
  • Hepatitis C virus (HCV)
  • Hepatitis E virus (HEV)
  • Virus–host interactions
  • Viral entry, replication and assembly mechanisms

Dr. Laurence Cocquerel is a virologist and CNRS Research Director (CNRS-DR1) / Professor at the Centre for Infection and Immunity of Lille (CIIL) in Lille, France.
She earned her Ph.D. in 2001 from the University of Paris VI (Sorbonne University), where her doctoral research focused on the HCV envelope glycoproteins. She subsequently completed postdoctoral training at Stanford University (USA) between 2001 and 2003, investigating the interaction between HCV glycoproteins and the host tetraspanin CD81, a key factor involved in viral entry.
In 2003, Dr. Cocquerel joined the Centre National de la Recherche Scientifique (CNRS) as a research scientist. For more than a decade, her research addressed the cellular mechanisms governing the entry step of the HCV lifecycle. Since 2015, her work has focused on the molecular and cellular mechanisms of the HEV lifecycle, with a particular emphasis on the ORF2 capsid protein.
Through her research, Dr. Cocquerel contributes to a better understanding of virus–host interactions and the fundamental processes that drive viral infection.