Chemical Biology of Flatworms: Identifying the molecular determinants of Schistosoma mansoni reproduction

Head of Team






The CBF team is involved in fundamental research on schistosomes using integrated chemical biology approaches. The main goal is the discovery and the development of novel therapeutic strategies against schistosomiasis.

The team is particularly focussed on the study of Schistosoma mansoni (S. mansoni). The life-cycle of S. mansoni, maintained by the team in a new dedicated lab requires two hosts, a fresh water snail Biomphalaria glabrata (B. glabrata) and a mammalian host (hamsters).

For more informations on S. mansoni life-cycle and how this worm is maintained in the lab, please visit our dedicated website: S. mansoni laboratory

The biology research of S. mansoni is strongly integrated with the expertise of the team in protein chemical synthesis and protein design, which also constitutes an important axis of research.

To have a large overview of our research in protein chemical synthesis, please visit our dedicated website: Protein chemical synthesis



Cyclic peptides can be produced in a few minutes by cyclization in a microfluidic system.

See our article in Nature Communications: Ollivier, O et al. Nature Comunications 2018

The life-cycle of Schistosoma mansoni


Protein chemical synthesis website

Schistosoma mansoni and Macrostomum lignano website

The website of the Protein Chemical Synthesis database