Publications
2018
(1) Cargoet, M.; Diemer, V.; Snella, B.; Desmet, R.; Blanpain, A.; Drobecq, H.; Agouridas, V.; Melnyk, O. Catalysis of Thiol-Thioester Exchange by Water-Soluble Alkyldiselenols Applied to the Synthesis of Peptide Thioesters and SEA-Mediated Ligation. Journal of Organic Chemistry 2018. in press
(2) Ollivier, N.; Toupy, T.; Hartkoorn, R. C.; Desmet, R.; Monbaliu, J. M.; Melnyk, O. Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides. Nature communications 2018, 9, 2847.
Open access: 10.1038/s41467-018-05264-8
(3) Mekki, M. S.; Mougel, A.; Vinchent, A.; Paquet, C.; Copin, M. C.; Leroy, C.; Kherrouche, Z.; Bonte, J. P.; Melnyk, O.; Vicogne, J. et al. Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors. Oncotarget 2018, 9, 27039-27058.
Open access: 10.18632/oncotarget.25472
(4) Grevelding, C. G.; Langner, S.; Dissous, C. Kinases: Molecular Stage Directors for Schistosome Development and Differentiation. Trends in parasitology 2018, 34, 246-260.
(5) Bayer, T.; Chakrabarti, A.; Lancelot, J.; Shaik, T. B.; Hausmann, K.; Melesina, J.; Schmidtkunz, K.; Marek, M.; Erdmann, F.; Schmidt, M.et al. Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis. ChemMedChem 2018, 13, 1517-1529.
(6) Simoben, C. V.; Robaa, D.; Chakrabarti, A.; Schmidtkunz, K.; Marek, M.; Lancelot, J.; Kannan, S.; Melesina, J.; Shaik, T. B.; Pierce, R. J. et al. A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing. Molecules 2018, 23.
Open access : 10.3390/molecules23030566
(7) Hamdi, A.; Enjalbal, C.; Drobecq, H.; Boukherroub, R.; Melnyk, O.; Ezzaouia, H.; Coffinier, Y. Fast and facile preparation of nanostructured silicon surfaces for laser desorption/ionization mass spectrometry of small compounds. Rapid communications in mass spectrometry 2018. in press