Publications


2020

Dewitte A, Bouvenot T, Pierre F, Ricard I, Pradel E, Barois N, Hujeux A, Bontemps-Gallo S, Sebbane F. A refined model of how Yersinia pestis produces a transmissible infection in its flea vector. PLoS Pathog. 2020. ;16(4):e1008440.

 

2019

Bontemps-Gallo S, Fernandez M, Dewitte A, Raphael E, Gherardini FC, Pradel E, Koch L, Biot F, Reboul A, Sebbane F. Nutrient depletion may trigger the Yersinia pestis OmpR-EnvZ regulatory system to promote flea-borne plague transmission. Mol Microbiol. 2019;112(5):1471‐1482.

 

Daniel C, Dewitte A, Poiret S, Marceau M, Simonet M, Marceau L, Descombes G, Boutillier D, Bennaceur N, Bontemps-Gallo S, Lemaître N, Sebbane F. Polymorphism in the Yersinia LcrV antigen enables immune escape from the protection conferred by an LcrV-secreting Lactococcus lactis. Front. Immunol. 2019 Aug 02;10:1030.


Gandon S, Heitzmann L, Sebbane F. To block or not to block: The adaptive manipulation of plague transmission. Evol Lett. 2019 Mar 27;3(2):152-161.


Koch L, Poyot T, Schnetterle M, Guillier S, Soulé E, Nolent F, Gorgé O, Neulat-Ripoll F, Valade E, Sebbane F, Biot F. Transcriptomic studies and assessment of Yersinia pestis reference genes in various conditions. Sci Rep. 2019 Feb 21;9(1):2501. 

 

2018

 

D'Ortenzio E, Lemaître N, Brouat C, Loubet P, Sebbane F, Rajerison M, Baril L, Yazdanpanah Y. Plague: Bridging gaps towards better disease control. Med Mal Infect. 2018 Aug;48(5):307-317.

 

2017

Lemaître N, Liang X, Najeeb J, Lee CJ, Titecat M, Leteurtre E, Simonet M, Toone EJ, Zhou P, Sebbane F. Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC. MBio. 2017 Jul 25;8(4).

 

2016

Daniel C, Titecat M, Poiret S, Cayet D, Boutillier D, Simonet M, Sirard JC, Lemaître N, Sebbane F. Characterization of the protective immune response to Yersinia pseudotuberculosis infection in mice vaccinated with an LcrV-secreting strain of Lactococcus lactis. Vaccine. 2016 Nov 11;34(47):5762-5767.


Titecat M, Liang X, Lee CJ, Charlet A, Hocquet D, Lambert T, Pagès JM, Courcol R, Sebbane F, Toone EJ, Zhou P, Lemaitre N. High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors. J Antimicrob Chemother. 2016 Oct;71(10):2874-82.


Lee CJ, Liang X, Wu Q, Najeeb J, Zhao J, Gopalaswamy R, Titecat M, Sebbane F, Lemaitre N, Toone EJ, Zhou P. Drug design from the cryptic inhibitor envelope. Nat Commun. 2016 Feb 25;7:10638.

 

2015

Quintard K, Dewitte A, Reboul A, Madec E, Bontemps-Gallo S, Dondeyne J, Marceau M, Simonet M, Lacroix JM, Sebbane F. Evaluation of the Role of the opgGH Operon in Yersinia pseudotuberculosis and Its Deletion during the Emergence of Yersinia pestis. Infect Immun. 2015 Sep;83(9):3638-47.


Goubard A, Loïez C, Abe J, Fichel C, Herwegh S, Faveeuw C, Porte R, Cayet D, Sebbane F, Penet S, Foligné B, Desreumaux P, Saito H, Sirard JC, Simonet M, Carnoy C. Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T cells. Infect Immun. 2015 May;83(5):2053-64.

 

2014

Bibi-Triki S, Li de la Sierra-Gallay I, Lazar N, Leroy A, Van Tilbeurgh H, Sebbane F, Pradel E. Functional and structural analysis of HicA3-HicB3, a novel toxin-antitoxin system of Yersinia pestis. J Bacteriol. 2014 Nov;196(21):3712-23.


Reboul A, Lemaître N, Titecat M, Merchez M, Deloison G, Ricard I, Pradel E, Marceau M, Sebbane F. Yersinia pestis requires the 2-component regulatory system OmpR-EnvZ to resist innate immunity during the early and late stages of plague. J Infect Dis. 2014 Nov 1;210(9):1367-75.


Pradel E, Lemaître N, Merchez M, Ricard I, Reboul A, Dewitte A, Sebbane F. New insights into how Yersinia pestis adapts to its mammalian host during bubonic plague. PLoS Pathog. 2014 Mar 27;10(3):e1004029.

 

2013

Gaillot O, Lemenand O, Marceau M, Simonet M. Proposed reclassification of Pasteurella lymphangitidis Sneath & Stevens 1990 as Yersinia pseudotuberculosis.  Int J Syst Evol Microbiol. 2013 Oct;63(Pt 10):3927-9.

Derbise A, Pierre F, Merchez M, Pradel E, Laouami S, Ricard I, Sirard JC, Fritz J, Lemaître N, Akinbi H, Boneca IG, Sebbane F. Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response. J Infect Dis. 2013 May 15;207(10):1535-43.


Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Médigue C, Parkhill J, Cruveiller S, Brosch R. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Nat Genet. 2013 Feb;45(2):172-9.

 

2012

Lemaître N, Ricard I, Pradel E, Foligné B, Courcol R, Simonet M, Sebbane F. Efficacy of ciprofloxacin-gentamicin combination therapy in murine bubonic plague. PLoS One. 2012;7(12):e52503.

 

2011

Chauvaux S, Dillies MA, Marceau M, Rosso ML, Rousseau S, Moszer I, Simonet M, Carniel E. In silico comparison of Yersinia pestis and Yersinia pseudotuberculosis transcriptomes reveals a higher expression level of crucial virulence determinants in the plague bacillus. Int J Med Microbiol. 2011 Feb;301(2):105-16.

 

2010

Sebbane F, Jarrett C, Gardner D, Long D, Hinnebusch BJ. Role of the Yersinia pestis yersiniabactin iron acquisition system in the incidence of flea-borne plague. PLoS One. 2010 Dec 17;5(12):e14379.


Moreau K, Lacas-Gervais S, Fujita N, Sebbane F, Yoshimori T, Simonet M, Lafont F. Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages. Cell Microbiol. 2010 Aug;12(8):1108-23.


Vadyvaloo V, Jarrett C, Sturdevant DE, Sebbane F, Hinnebusch BJ. Transit through the flea vector induces a pretransmission innate immunity resistance phenotype in Yersinia pestis. PLoS Pathog. 2010 Feb 26;6(2):e1000783.


Ayyadurai S, Sebbane F, Raoult D, Drancourt M. Body lice, yersinia pestis orientalis, and black death. Emerg Infect Dis. 2010 May;16(5):892-3.


Van Maele L, Carnoy C, Cayet D, Songhet P, Dumoutier L, Ferrero I, Janot L, Erard F, Bertout J, Leger H, Sebbane F, Benecke A, Renauld JC, Hardt WD, Ryffel B, Sirard JC. TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. J Immunol. 2010 Jul 15;185(2):1177-85.

 

2009

Sebbane F, Jarrett C, Gardner D, Long D, Hinnebusch BJ. The Yersinia pestis caf1M1A1 fimbrial capsule operon promotes transmission by flea bite in a mouse model of bubonic plague. Infect Immun. 2009 Mar;77(3):1222-9.

Daniel C, Sebbane F, Poiret S, Goudercourt D, Dewulf J, Mullet C, Simonet M, Pot B. Protection against Yersinia pseudotuberculosis infection conferred by a Lactococcus lactis mucosal delivery vector secreting LcrV. Vaccine. 2009 Feb 18;27(8):1141-4.


Arafah S, Rosso ML, Rehaume L, Hancock RE, Simonet M, Marceau M. An iron-regulated LysR-type element mediates antimicrobial peptide resistance and virulence in Yersinia pseudotuberculosis. Microbiology. 2009 Jul;155(Pt 7):2168-81.